Introduction of the Director

Eric Westhof is a member of the French Academy of Sciences and the German Academy of Sciences (Leopoldina), a member of the European Molecular Biology Organization (EMBO), a member of the Association of Chinese and French Experts, a principal researcher at the Wenzhou Institute of the University of the Chinese Academy of Sciences (UCAS), a visiting professor at the Southwest University of China (SWU), a professor emeritus of the University of Strasbourg (UNIS), and the president of the French Society of Gutenberg Representative.

For his outstanding academic achievements, he has received several French and international awards, including the Jacques Monod Prize, the Charles Leopold Meyer Prize, the Distinguished Service Award of the RNA Society, the Fyodor Lynn Medal of the German Society for Biochemistry and Molecular Biology, the Wang Yingjian Medal of the Shanghai Institute of Biochemistry of the Chinese Academy of Sciences, and the Rolf Sammet Prize of the Johann Wolfgang Goethe University in Frankfurt, Datta Medal of the European Union of Biochemistry, and the Lifetime Achievement Award of the International RNA Society.

According to Web of Science, he has published 477 papers (32,760 citations with an h-index of 97), 23 in the Nature series of journals and 11 in Science. He was ranked 685th worldwide and 11th in France in the 2024 Research.com ranking of scientists in biology and biochemistry and received the Leaders in Biology and Biochemistry Award. He is ranked 5th in the field of RNA in the 2022 ScholarGPS Global Highly Ranked Scholars. He has co-edited four books and serves on the editorial boards of several internationally recognized academic journals, including Associate Editor of RNA, Executive Editor of Oxford University Press Nucleic Acids Research, Executive Editor of Wiley Journal of Molecular Recognition, and Executive Editor of Elsevier Biochemistry and Biophysics Research Letters.

Projects and Research

His research activities focus on the relationship between sequence, three-dimensional structure, evolution and function of RNA molecules. The goal is to understand RNA evolution and the ongoing interaction between sequence changes and RNA structure/activity. Through comparative crystallographic and bioinformatics approaches, he studied RNA folding and biological functions. To this end, he introduced the "Leontis-Westhof" RNA base pair nomenclature to annotate all types of base pairs in nucleic acids, and in 2010 he launched RNA-Puzzles, an international competition to evaluate blind predictions of 3D RNA structure. The project is part of an ongoing effort to extract maximum information from structure-anchored comparative sequence analysis. Because sequence alignment and 3D assembly of RNA modules have enabled me to predict large catalytic RNAs, such as those of group I introns and RNaseP, he hopes to continue my research along these lines. Indeed, RNA sequence alignments are extremely rich; they allow the identification of conserved helix lengths, unpaired regions, anchor points, conserved residues, semi-conserved residues, concatenated regions, RNA modules and conserved hairpins, conserved or exchanged non-Watson-Crick pairs, as well as key structural residues (e.g., U-turns). The project will include (1) development of methods and tools for generating structure comparisons, i.e., experimental structure-based comparisons, and (2) automation of the overall process.

Conditions for recruitment

1. Hold PhD in molecular chemistry, molecular biology, structural biology or bioinformatics;

2. Good reading and writing skills in English ;

3. Ability to work independently on a computer, and proficiency in at least one programming language;

4. Skills in molecular calculations or sequence alignments are advantageous.

Compensation

The postdoctoral students will be admitted to the postdoctoral mobile station of University of Chinese Academy of Sciences (UCAS), and the fresh graduates will enjoy the same policies as those of NUST, such as staying in Beijing and working place is in Wenzhou, and the outstanding ones can be recruited as the associate researcher of the subject group after leaving the station. The postdoctoral positions are divided into three categories (A, B and C), and the salaries are as follows:

A: 40W + tutor's allowance (0-18W) + performance incentive + five insurance and one gold.

B: 30W + mentor subsidy (0-12W) + performance incentives + five insurance and one pension

C: Negotiable mentor + performance incentive + five insurance and one gold

Talent apartment can be rented, about 1500RMB/month (Postdoctoral fellows who leave the station and stay to work in Wenzhou can buy 60% discount talent housing)

Application

1. Please send a detailed CV in Chinese or English (photo, birthplace, education and work experience, list of achievements in scientific research with supporting documents, etc.).

2. Send the electronic version of the documents to eric@wiucas.ac.cn ou cl@wiucas.ac.cn

負(fù)責(zé)人介紹

埃里克·韋斯托夫（EricWesthof）是法國科學(xué)院院士，德國科學(xué)院院士，歐洲分子生物學(xué)組織（EMBO）成員，法國法中高級人才交流協(xié)會（AEFC）會員，國科溫州研究院首席研究員，西南大學(xué)客座教授，斯特拉斯堡大學(xué)名譽(yù)教授，法國古騰堡（Gutenberg）科學(xué)家聯(lián)盟執(zhí)行主席。

因其卓越的學(xué)術(shù)成就，他獲得了多個法國和國際獎項，包括雅克·莫諾獎、查爾斯-萊奧波德·邁耶獎、RNA協(xié)會杰出服務(wù)獎、德國生物化學(xué)和分子生物學(xué)協(xié)會費(fèi)奧多·林恩獎?wù)隆⒅袊茖W(xué)院上海生物化學(xué)研究所王應(yīng)睞獎、法蘭克福約翰·沃爾夫?qū)じ璧麓髮W(xué)羅爾夫·薩梅特獎、歐洲生物化學(xué)聯(lián)合會達(dá)塔獎?wù)乱约皣HRNA學(xué)會終身成就獎。
根據(jù)WebofScience，他發(fā)表了477篇論文（32,760次引用，h指數(shù)為97），其中23篇在《自然》系列期刊上，11篇在《科學(xué)》上。他在2024年Research.com的生物學(xué)和生物化學(xué)領(lǐng)域科學(xué)家排名中位列全球第685位，法國第11位，并獲得生物學(xué)和生物化學(xué)領(lǐng)域領(lǐng)導(dǎo)者獎。在2022年ScholarGPS全球高排名學(xué)者中，他在RNA領(lǐng)域排名第五。他合編了4本書，并擔(dān)任多個國際知名學(xué)術(shù)期刊的編輯委員會成員，包括《RNA》科學(xué)的副主編、牛津大學(xué)出版社《核酸研究》的執(zhí)行編輯、威利《分子識別雜志》的執(zhí)行編輯和愛思唯爾《生物化學(xué)和生物物理研究通訊》的執(zhí)行編輯。

項目與研究
他的研究集中在RNA分子的序列、三維結(jié)構(gòu)、進(jìn)化和功能之間的關(guān)系。目標(biāo)是理解RNA的進(jìn)化以及序列變化與RNA結(jié)構(gòu)/活性之間的持續(xù)互動。通過比較晶體學(xué)和生物信息學(xué)的方法，他研究了RNA的折疊和生物功能。為此，他引入了“Leontis-Westhof”RNA堿基配對命名法，以注釋核酸中的所有類型堿基對，并在2010年發(fā)起了RNA-Puzzles，這是一項評估3DRNA結(jié)構(gòu)盲預(yù)測的國際競賽。該項目是從結(jié)構(gòu)錨定的比較序列分析中提取最大信息的持續(xù)努力的一部分。因為序列比對和RNA模塊的3D組裝使他能夠預(yù)測大型催化RNA，如I組內(nèi)含子和RNaseP的RNA，他希望沿這些方向繼續(xù)研究。事實上，RNA序列比對極其豐富；它們允許識別保守的螺旋長度、未配對區(qū)域、錨點、保守殘基、半保守殘基、協(xié)變區(qū)域、RNA模塊和保守發(fā)夾、非Watson-Crick配對的保守或交換，以及關(guān)鍵結(jié)構(gòu)殘基（如U型轉(zhuǎn)折）。項目將包括（1）開發(fā)用于生成結(jié)構(gòu)比對的方法和工具，即基于實驗結(jié)構(gòu)的比對；（2）整體過程的自動化。

招聘條件
擁有分子化學(xué)、分子生物學(xué)、結(jié)構(gòu)生物學(xué)或生物信息學(xué)的博士學(xué)位；

良好的英語閱讀和寫作能力；
具備良好的獨(dú)立電腦工作能力，掌握至少一種計算機(jī)語言；
具備分子計算或序列比對的能力者優(yōu)先。

薪酬
博士后：博后入中國科學(xué)院大學(xué)博士后流動站，應(yīng)屆生享受國科大留京戶口等同等政策，工作地點在溫州，出站后優(yōu)秀者可應(yīng)聘課題組副研究員。博士后分為三類(A類、B類和C類)，薪資如下：

A：40W+導(dǎo)師補(bǔ)貼(0-18W)+績效獎勵+五險一金
B：30W+導(dǎo)師補(bǔ)貼(0-12W)+績效獎勵+五險一金
C：導(dǎo)師面議+績效獎勵+五險一金
可租住人才公寓，約1500元/月左右（博后出站留溫工作，可購買6折人才房）
申請
1.請?zhí)峤恢形幕蛴⑽牡脑敿?xì)簡歷（照片、出生地、教育和工作經(jīng)歷、科研成果清單及支持文件等）。

2.郵件主題命名為:"Name-Postdoctoral fellowship".將電子版文件發(fā)送至eric@wiucas.ac.cn或cl@wiucas.ac.cn，郵件主題命名為：“姓名-博士后招聘”

信息來源于網(wǎng)絡(luò)，如有變更請以原發(fā)布者為準(zhǔn)。

來源鏈接：

https://www.wiucas.ac.cn/recruitment/keyan/2024/2009.html

更多最新博士后招收資訊請關(guān)注高才博士后微信公眾號（微信號：bshjob）。