一、中心簡介
首都醫學科學創新中心（簡稱創新中心）是北京市新成立的具有獨立法人資格的新型研發機構。創新中心以推動醫學科學發展、改善人類健康為目標，開展生物醫學研究，致力于提升醫學科學創新與成果轉化能力，提高疾病診斷和治療水平。我們將匯聚世界高水平科學家，與首都醫學教育和科學研究優質資源緊密合作，打造多學科交叉融合的科研平臺，綜合自由探索、醫學目標導向、有組織科研等途徑，實踐新型科研模式和體制機制，逐步推進醫教研產的深度融合，培養適應醫學科學創新發展的優秀人才。
二、實驗室介紹
首都醫學科學創新中心免疫研究所孫少聰實驗室招聘博士后或副研究員以開展癌癥免疫和自身免疫的基礎和轉化研究。本實驗室長期致力于T細胞的功能和機制研究。使用信號轉導，CRISPR基因篩選，單細胞RNA測序，和基因敲除小鼠等多種方法研究T細胞激活，分化，效應功能和耗竭的分子機理，從而鑒定關鍵性T細胞調節因子。近期工作還包括運用生物信息學手段分析癌癥患者腫瘤測序數據庫，鑒定癌癥免疫調節因子，然后用小鼠模型進行機理研究。自身免疫研究包括多發行硬化癥，SLE，和腸炎的小鼠模型。
三、代表性論文
Nature Cell Biology 24: 1165-1176, 2022, PMID: 35773432
Nature Immunology 22: 193-204, 2021, PMID: 33398181
Nature Cell Biology 21: 1604-1614, 2019, PMID: 31792381
Nature Immunology 20: 879-889, 2019, PMID: 31182807
Nature Immunology 19: 1224-1235, 2018, PMID: 30250187
Nature 545: 365-369, 2017, PMID: 28489822
Nature Immunology 17: 259-268, 2016, PMID: 26808229
Nature Immunology 15: 562-570, 2014, PMID: 24777531
Immunity 40: 692-705, 2014, PMID: 24792914
Nature Medicine 19: 595-602, 2013, PMID: 23603814
Nature 494: 371-374, 2013, PMID: 23334419
四、博士后/副研究員
01、崗位職責
1.獨立開展和參與實驗室課題研究工作；
2.協助PI指導研究生工作。
02、任職要求
1.具有免疫學相關領域研究背景，即將或已經獲得博士學位；副研究員需要有博士后研究經歷；
2.具備獨立開展科研工作和指導研究生能力，具有科研熱情和嚴謹的科研態度；
3.具備熟練的英文交流和讀寫能力，可以獨立撰寫英文論文；
4.有扎實的免疫學、信息生物學、小鼠腫瘤免疫或自身免疫模型試驗背景者優先考慮。
五、福利待遇
1.根據應聘者的工作經驗和能力，提供具有市場競爭力的薪酬（詳情面談）；
2.享受五險一金、帶薪年假、體檢和補充醫療保險等；
3.支持個人職業發展，提供必要的工作相關專業培訓。
六、申請方法
應聘者請將個人簡歷、研究興趣或計劃，以及2-3名推薦人的姓名及聯系方式，以及其他能證明科研能力的相關電子文件發送到郵箱 ssun@cimrbj.ac.cn，請【點擊下方“立即投遞/投遞簡歷”，即刻進行職位報名】，郵件主題請注明“應聘者名字+具體應聘職位”。
聯系人：
聯系地址：北京市豐臺區右安門外西頭條10號-首都醫學科學創新中心
本招聘長期有效，至招聘到合適人選為止。
ABOUT CIMR
Chinese Institutes for
Medical Research (CIMR) is a newly founded institution dedicated to fundamental
and translational medical research.The CIMR is located at the main campus of
the
Laboratory Introduction
The laboratory of Shao-Cong Sun at the Chinese Institutes for Medical Research (CIMR) is recruiting motivated Postdoctoral Fellows and Research Associate Investigators to conduct basic and translational research in Cancer Immunology and Autoimmunity.A major focus of the lab is to study the molecular mechanisms that regulate T cell activation, differentiation, effector function, and exhaustion using a variety of cutting-edge techniques, such as signal transduction, CRISPR library screening, single-cell RNA sequencing, and knockout mouse models.Our recent work also includes the use of bioinformatics to analyze tumor sequencing databases of cancer patients, identify cancer immunomodulators, and then conduct mechanistic studies using mouse models.Autoimmune studies include mouse models of multiple sclerosis, SLE, and colitis.Professor Sun's team has made many significant contributions in this field, including the discovery of key factors regulating T cell functions in autoimmunity and cancer immunity.Our work also has strong translational potential and plays an important guiding role in drug development and disease treatment.The laboratory also uses mouse models of cancer immunotherapy to conduct translational studies and explore improved methods of immunotherapy.
Representative Publications
Nature Cell Biology 24: 1165-1176, 2022, PMID: 35773432
Nature Immunology 22: 193-204, 2021, PMID: 33398181
Nature Cell Biology 21: 1604-1614, 2019, PMID: 31792381
Nature Immunology 20: 879-889, 2019, PMID: 31182807
Nature Immunology 19: 1224-1235, 2018, PMID: 30250187
Nature 545: 365-369, 2017, PMID: 28489822
Nature Immunology 17: 259-268, 2016, PMID: 26808229
Nature Immunology 15: 562-570, 2014, PMID: 24777531
Immunity 40: 692-705, 2014, PMID: 24792914
Nature Medicine 19: 595-602, 2013, PMID: 23603814
Nature 494: 371-374, 2013, PMID: 23334419
Open Positions
Postdoctoral Fellows /
Research Associate Investigators
Main Responsibilities
a.Carrying out research projects independently.
b.Assisting PI to mentor graduate student.
Qualifications
a.With research background in immunology related biomedical fields, either about to obtain or having already obtained a doctoral degree; postdoctoral experience is required for research associate investigator position.
b.With motivation and ability to independently carry out research projects and supervise graduate students, and have strong motivation in scientific research.
c.Proficient in English reading, writing, and daily communication; capable of writing papers in English.
d.Those with solid background in immunology, bioinformatics, mouse models of cancer immunity or autoimmunity, or CRISPR screen will be given priority.
Welfare Treatment
a.Provide competitive salary based on the applicant’s work experience and ability (salary negotiable).
b.Provide social insurance and housing fund, supplementary medical insurance, physical examination and paid annual leave.
c.Support career development, provide relevant professional guidance.
How to apply
To apply, please send personal resume, research interest or plan, the names and contacts of 2-3 referees and other materials demonstrating research capabilities to ssun@cimrbj.ac.cn, and indicate the applicant's name and specific job position in the email subject.
Contact person: Dr.Sun
This recruitment is valid for the long term until a suitable candidate is recruited.
信息來源于網絡，如有變更請以原發布者為準。
來源鏈接：
https://mp.weixin.qq.com/s/826vE_T8fw2KtdqX0VhpQQ
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